Synake

PROLOU the secret ingredient - SYNAKE

SYNAKE is a new anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of waglerin 1, a peptide that is found in the venom of the Temple Viper.

The most advanced anti wrinkle cream on the market today

Wrinkles are reduced in a short period with Synake.

Synake is particularly effective against expression lines.

Synake is an intense ageing anti-wrinkle cream.

EFFICACY TESTS

In vitro tests:

By measuring the contraction of the innervated muscle cell as a function of the incubation time, we can demonstrate the efficacy of the Synake tripetide in vitro, based on a 5ml concentration.

Synake reduces muscle cell concentration and the action is reversible.

In vivi tests:

By comparing the Synake (4%) against a placebo, it allowed us to measure the smoothness and overall effectiveness. For 28 days the cream was applied twice daily.

Synake - Age Killing Effect.

The smoothing effect (Ra) was measured on 80% of the volunteers and the anti-wrinkle effect (Rz, Rt) measured on 73% of the volunteers.

Results showed up to a 52% wrinkle decrease after applying it for 28 days.

The Real "Age-Killing-Effect"

Synake: synthetic substance mimics snake venom activity

Snake venom can be deadly to humans but it can also be used to heal. ‘Wrinkle-killer’ to help improve the facial appearance of both men and women. Synake is a synthetic substance which mimics part of a polypeptide found in the venom of a Temple Viper.

When communicating such as frowning, speaking and laughing, we us about 60 muscles in our face. Over time this causes wrinkles in the deeper layers. But know a treatment is available to get rid of these wrinkles without having to have cosmetic surgery or Botox.

Synake is the alternative to using using these extremes. The new synthetic Tripeptide mimics the effect of Waglerin-1. The viper, from which it is found, owes its name to the German herpe- tologist Johann Georg Wagler. He found that it inhibits neuromuscular communication. Once the snake has bitten its prey, the venom blocks the nerve pulses therefore paralysing its victim. This causes death, but the synthetic imitation which is found in Syn-ake, means part of the venom causes the muscles contractions to relax. The end result- smooth, replenished looking skin.

Its excellent formula reduces wrinkles and smoothes out the surface in just a few days. The in vivo studies dealing with crow's feet confirmed the efficiency of the product. It found that using Syake of a concentration of 5ml, reduces the frequency of muscle contractions in innervated muscles by up to 82% (p<O.05) within 2hours.

Snake venom research by Pentapharm in Brazil has enabled this unique treatment to come about and be available today. For 30 years snake venom has been used for therapeutic diagnostic purposes. An example is the Lance Adder venom found in South America. By utilizing the anti-coagulant parts of the snake, Pentapharm is able to breed around 10,000 in their snake farm in Brazil.

The venom is milked locally and then purified in Switzerland.

The production of Synake allows the snake farm to stay open and is totally safe . Indisputably, ecology-friendly and totally without risk, during production (in line with our "Responsible Care Program"). It contains no preservative and is considered absolutely safe for use in cosmetic products.

Synake